Eradication of CML stem cells

Por Carter, Bing Z., Andreeff, Michael
Publicado no Oncoscience (2016)

Bone marrow niche-mediated survival of leukemia stem cells in acute myeloid leukemia: Yin and Yang

Por Zhou, Hong-Sheng, Carter, Bing Z., Andreeff, Michael
Publicado no Cancer Biol Med (2016)

The elusive CML stem cell: does it matter and how do we eliminate it?

Por Carter, Bing Z., Mak, Duncan D., Cortes, Jorge, Andreeff, Michael
Publicado em 2010

Dasatinib Induces Autophagic Cell Death in Human Ovarian Cancer

Por Le, Xiao-Feng, Mao, Weiqun, Lu, Zhen, Carter, Bing Z., Bast, Robert C.
Publicado em 2010

XIAP Downregulation Promotes Caspase-dependent Inhibition of Proteasome Activity in AML Cells

Por Carter, Bing Z., Mak, Duncan H., Wang, Zhiqiang, Ma, Wencai, Mak, Po Yee, Andreeff, Michael, Davis, R. Eric
Publicado em 2013

Apoptosis suppressor ARC modulates SMAC mimetic-induced cell death through BIRC2/MAP3K14 signalling in acute myeloid leukaemia

Por Mak, Po Yee, Mak, Duncan H., Ruvolo, Vivian, Jacamo, Rodrigo, Kornblau, Steven M., Andreeff, Michael, Carter, Bing Z.
Publicado no Br J Haematol (2014)

Inhibition of KSP by ARRY-520 Induces Cell Cycle Block and Cell Death via the Mitochondrial Pathway in AML Cells

Por Carter, Bing Z., Mak, Duncan H., Woessner, Richard, Gross, Stefan, Schober, Wendy D., Estrov, Zeev, Kantarjian, Hagop, Andreeff, Michael
Publicado em 2009

MRx102, a triptolide derivative, has potent antileukemic activity in vitro and in a murine model of AML

Por Carter, Bing Z., Mak, Duncan H., Shi, Yuxie, Fidler, John M., Chen, Rong, Ling, Xiaoyang, Plunkett, William, Andreeff, Michael
Publicado em 2011

Therapeutic Molecular Targeting of 15-Lipoxygenase-1 in Colon Cancer

Por Wu, Yuanqing, Fang, Bingliang, Yang, Xiulan Q, Wang, Li, Chen, Dongning, Krasnykh, Victor, Carter, Bing Z, Morris, Jeffrey S, Shureiqi, Imad
Publicado em 2008

Triptolide induces cell death independent of cellular responses to imatinib in blast crisis CML cells including quiescent CD34(+) primitive progenitor cells

Por Mak, Duncan H., Schober, Wendy D., Chen, Wenjing, Konopleva, Marina, Cortes, Jorge, Kantarjian, Hagop M., Andreeff, Michael, Carter, Bing Z.
Publicado em 2009

Simultaneous activation of p53 and inhibition of XIAP enhance the activation of apoptosis signaling pathways in AML

Por Carter, Bing Z., Mak, Duncan H., Schober, Wendy D., Koller, Erich, Pinilla, Clemencia, Vassilev, Lyubomir T., Reed, John C., Andreeff, Michael
Publicado em 2010

Activation of Apoptosis Signaling Eliminates CD34(+) Progenitor Cells in Blast Crisis CML Independent of Response to Tyrosine Kinase Inhibitors

Por Mak, Duncan H., Wang, Rui-Yu, Schober, Wendy D., Konopleva, Marina, Cortes, Jorge, Kantarjian, Hagop, Andreeff, Michael, Carter, Bing Z.
Publicado em 2011

Triptolide induces caspase-dependent cell death mediated via the mitochondrial pathway in leukemic cells

Por Carter, Bing Z., Mak, Duncan H., Schober, Wendy D., McQueen, Teresa, Harris, David, Estrov, Zeev, Evans, Randall L., Andreeff, Michael
Publicado em 2006

Regulation of survivin expression through Bcr-Abl/MAPK cascade: targeting survivin overcomes imatinib resistance and increases imatinib sensitivity in imatinib-responsive CML cells

Por Carter, Bing Z., Mak, Duncan H., Schober, Wendy D., Cabreira-Hansen, Maria, Beran, Miloslav, McQueen, Teresa, Chen, Wenjing, Andreeff, Michael
Publicado em 2006

Triptolide sensitizes AML cells to TRAIL-induced apoptosis via decrease of XIAP and p53-mediated increase of DR5

Por Carter, Bing Z., Mak, Duncan H., Schober, Wendy D., Dietrich, Martin F., Pinilla, Clemencia, Vassilev, Lyubomir T., Reed, John C., Andreeff, Michael
Publicado em 2008

Therapeutic targeting of the MEK/MAPK signal transduction module in acute myeloid leukemia

Por Milella, Michele, Kornblau, Steven M., Estrov, Zeev, Carter, Bing Z., Lapillonne, Hélène, Harris, David, Konopleva, Marina, Zhao, Shourong, Estey, Elihu, Andreeff, Michael
Publicado em 2001

XIAP antisense oligonucleotide (AEG35156) achieves target knockdown and induces apoptosis preferentially in CD34(+)38(−) cells in a phase 1/2 study of patients with relapsed/refrac...

Por Carter, Bing Z., Mak, Duncan H., Morris, Stephen J., Borthakur, Gautam, Estey, Elihu, Byrd, Anna L., Konopleva, Marina, Kantarjian, Hagop, Andreeff, Michael
Publicado em 2011

miR-150 exerts antileukemia activity in vitro and in vivo through regulating genes in multiple pathways

Por Fang, Zhi Hong, Wang, Si Li, Zhao, Jin Tao, Lin, Zhi Juan, Chen, Lin Yan, Su, Rui, Xie, Si Ting, Carter, Bing Z, Xu, Bing
Publicado no Cell Death Dis (2016)

Expression of ARC (apoptosis repressor with caspase recruitment domain), an antiapoptotic protein, is strongly prognostic in AML

Por Carter, Bing Z., Qiu, Yi Hua, Zhang, Nianxiang, Coombes, Kevin R., Mak, Duncan H., Thomas, Deborah A., Ravandi, Farhad, Kantarjian, Hagop M., Koller, Erich, Andreeff, Michael, Kornblau, Steven M.
Publicado em 2011

Synergistic effects of p53 activation via MDM2 inhibition in combination with inhibition of Bcl-2 or Bcr-Abl in CD34(+) proliferating and quiescent chronic myeloid leukemia blast c...

Por Carter, Bing Z., Mak, Po Yee, Mak, Duncan H., Ruvolo, Vivian R., Schober, Wendy, McQueen, Teresa, Cortes, Jorge, Kantarjian, Hagop M., Champlin, Richard E., Konopleva, Marina, Andreeff, Michael
Publicado no Oncotarget (2015)