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XIAP Downregulation Promotes Caspase-dependent Inhibition of Proteasome Activity in AML Cells

To further understand the role of XIAP in acute myeloid leukemia (AML), we suppressed XIAP expression by antisense oligonucleotides and determined the effect on gene expression profiles and biological pathways. XIAP inhibition upregulated expression of proteasome genes in a manner similar to the pro...

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Detalhes bibliográficos
Main Authors: Carter, Bing Z., Mak, Duncan H., Wang, Zhiqiang, Ma, Wencai, Mak, Po Yee, Andreeff, Michael, Davis, R. Eric
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3700666/
https://ncbi.nlm.nih.gov/pubmed/23669290
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.leukres.2013.04.018
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