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XIAP Downregulation Promotes Caspase-dependent Inhibition of Proteasome Activity in AML Cells

To further understand the role of XIAP in acute myeloid leukemia (AML), we suppressed XIAP expression by antisense oligonucleotides and determined the effect on gene expression profiles and biological pathways. XIAP inhibition upregulated expression of proteasome genes in a manner similar to the pro...

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Bibliografische gegevens
Hoofdauteurs: Carter, Bing Z., Mak, Duncan H., Wang, Zhiqiang, Ma, Wencai, Mak, Po Yee, Andreeff, Michael, Davis, R. Eric
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2013
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3700666/
https://ncbi.nlm.nih.gov/pubmed/23669290
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.leukres.2013.04.018
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