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Dasatinib Induces Autophagic Cell Death in Human Ovarian Cancer

BACKGROUND: Dasatinib, an inhibitor of Src/Abl family kinases, can inhibit tumor growth of a number of solid tumors. However, the effect and mechanism of action of dasatinib in human ovarian cancer cells remains unknown. METHODS: Dasatinib-induced autophagy was determined by acridine orange staining...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Le, Xiao-Feng, Mao, Weiqun, Lu, Zhen, Carter, Bing Z., Bast, Robert C.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2010
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2975555/
https://ncbi.nlm.nih.gov/pubmed/20629079
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cncr.25426
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