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The Role of p27(Kip1) in Dasatinib-Enhanced Paclitaxel Cytotoxicity in Human Ovarian Cancer Cells

BACKGROUND: Less than 50% of ovarian cancers respond to paclitaxel. Effective strategies are needed to enhance paclitaxel sensitivity. METHODS: A library of silencing RNAs (siRNAs) was used to identify kinases that regulate paclitaxel sensitivity in human ovarian cancer SKOv3 cells. The effect of da...

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Detalhes bibliográficos
Main Authors: Le, Xiao-Feng, Mao, Weiqun, He, Guangan, Claret, Francois-Xavier, Xia, Weiya, Ahmed, Ahmed Ashour, Hung, Mien-Chie, Siddik, Zahid H., Bast, Robert C.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3176777/
https://ncbi.nlm.nih.gov/pubmed/21813412
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jnci/djr280
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