Φορτώνει......
Triptolide induces cell death independent of cellular responses to imatinib in blast crisis CML cells including quiescent CD34(+) primitive progenitor cells
The advent of Bcr-Abl tyrosine kinase inhibitors (TKIs) has revolutionized the treatment of CML. However, resistance evolves due to BCR-ABL mutations and other mechanisms. Furthermore, patients with blast crisis (BC) CML are less responsive and quiescent CML stem cells are insensitive to these inhib...
Αποθηκεύτηκε σε:
| Κύριοι συγγραφείς: | , , , , , , , |
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| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
2009
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2754862/ https://ncbi.nlm.nih.gov/pubmed/19723894 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1535-7163.MCT-09-0386 |
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