Regulation of HIF-1α signaling and chemoresistance in acute lymphocytic leukemia under hypoxic conditions of the bone marrow microenvironment

Overcoming resistance to chemotherapy is the main therapeutic challenge in the treatment of acute lymphocytic leukemia (ALL). Interactions between leukemia cells and the microenvironment promote leukemia cell survival and confer resistance to chemotherapy. Hypoxia is an integral component of bone ma...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Κύριοι συγγραφείς: Frolova, Olga, Samudio, Ismael, Benito, Juliana Maria, Jacamo, Rodrigo, Kornblau, Steven M., Markovic, Ana, Schober, Wendy, Lu, Hongbo, Qiu, Yi Hua, Buglio, Daniela, McQueen, Teresa, Pierce, Sherry, Shpall, Elizabeth, Konoplev, Sergej, Thomas, Deborah, Kantarjian, Hagop, Lock, Richard, Andreeff, Michael, Konopleva, Marina
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: Landes Bioscience 2012
Θέματα:
Research Paper
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3414410/
https://ncbi.nlm.nih.gov/pubmed/22785211
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cbt.20838
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