Situs inversus and embryonic ciliary morphogenesis defects in mouse mutants lacking the KIF3A subunit of kinesin-II

The embryonic cellular events that set the asymmetry of the genetic control circuit controlling left-right (L-R) axis determination in mammals are poorly understood. New insight into this problem was obtained by analyzing mouse mutants lacking the KIF3A motor subunit of the kinesin-II motor complex....

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Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Marszalek, Joseph R., Ruiz-Lozano, Pilar, Roberts, Elizabeth, Chien, Kenneth R., Goldstein, Lawrence S. B.
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 1999
Assuntos:	Biological Sciences
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC21813/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10220415/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.96.9.5043
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