Deletion of Smad4 in Fibroblasts Leads to Defective Chondrocyte Maturation and Cartilage Production in a TGF Type II Receptor Independent Manner

Por Teng, Yingqi, Kanasaki, Keizo, Bardeesy, Nabeel, Sugimoto, Hikaru, Kalluri, Raghu
Publicado em 2011

Human tumstatin and human endostatin exhibit distinct antiangiogenic activities mediated by αvβ3 and α5β1 integrins

Por Sudhakar, Akulapalli, Sugimoto, Hikaru, Yang, Changqing, Lively, Julie, Zeisberg, Michael, Kalluri, Raghu
Publicado em 2003

Fibroblasts in Kidney Fibrosis Emerge via Endothelial-to-Mesenchymal Transition

Por Zeisberg, Elisabeth M., Potenta, Scott E., Sugimoto, Hikaru, Zeisberg, Michael, Kalluri, Raghu
Publicado em 2008

Bone-marrow-derived stem cells repair basement membrane collagen defects and reverse genetic kidney disease

Por Sugimoto, Hikaru, Mundel, Thomas M., Sund, Malin, Xie, Liang, Cosgrove, Dominic, Kalluri, Raghu
Publicado em 2006

Identification of Epithelial to Mesenchymal Transition as a Novel Source of Fibroblasts in Intestinal Fibrosis

Por Flier, Sarah N., Tanjore, Harikrishna, Kokkotou, Efi G., Sugimoto, Hikaru, Zeisberg, Michael, Kalluri, Raghu
Publicado em 2010

Identification of amino acids essential for the antiangiogenic activity of tumstatin and its use in combination antitumor activity

Por Eikesdal, Hans Petter, Sugimoto, Hikaru, Birrane, Gabriel, Maeshima, Yohei, Cooke, Vesselina G., Kieran, Mark, Kalluri, Raghu
Publicado em 2008

Human α1 type IV collagen NC1 domain exhibits distinct antiangiogenic activity mediated by α1β1 integrin

Por Sudhakar, Akulapalli, Nyberg, Pia, Keshamouni, Venkateshwar G., Mannam, Arjuna P., Li, Jian, Sugimoto, Hikaru, Cosgrove, Dominic, Kalluri, Raghu
Publicado em 2005

Characterization of the anti-angiogenic properties of arresten, an α1β1 integrin dependent collagen-derived tumor suppressor

Por Nyberg, Pia, Xie, Liang, Sugimoto, Hikaru, Colorado, Pablo, Sund, Malin, Holthaus, Kathryn, Sudhakar, Akulapalli, Salo, Tuula, Kalluri, Raghu
Publicado em 2008

Origin and Function of Myofibroblasts in Kidney Fibrosis

Por LeBleu, Valerie S., Taduri, Gangadhar, O’Connell, Joyce, Teng, Yingqi, Cooke, Vesselina G., Woda, Craig, Sugimoto, Hikaru, Kalluri, Raghu
Publicado em 2013

Identification of Human Epididymis Protein-4 as a Novel Fibroblast-Derived Mediator of Fibrosis

Por LeBleu, Valerie S., Teng, Yingqi, O’Connell, Joyce T., Charytan, David, Müller, Gerhard A, Müller, Claudia A, Sugimoto, Hikaru, Kalluri, Raghu
Publicado no Nat Med (2013)

Type XVIII collagen is essential for survival during acute liver injury in mice

Por Duncan, Michael B., Yang, Changqing, Tanjore, Harikrishna, Boyle, Patrick M., Keskin, Doruk, Sugimoto, Hikaru, Zeisberg, Michael, Olsen, Bjorn R., Kalluri, Raghu
Publicado em 2013

EMT Program is Dispensable for Metastasis but Induces Chemoresistance in Pancreatic Cancer

Por Zheng, Xiaofeng, Carstens, Julienne L., Kim, Jiha, Scheible, Matthew, Kaye, Judith, Sugimoto, Hikaru, Wu, Chia-Chin, LeBleu, Valerie S., Kalluri, Raghu
Publicado no Nature (2015)

Physiological levels of tumstatin, a fragment of collagen IV α3 chain, are generated by MMP-9 proteolysis and suppress angiogenesis via αVβ3 integrin

Por Hamano, Yuki, Zeisberg, Michael, Sugimoto, Hikaru, Lively, Julie C., Maeshima, Yohei, Yang, Changqing, Hynes, Richard O., Werb, Zena, Sudhakar, Akulapalli, Kalluri, Raghu
Publicado em 2003

Targeting vascular pericytes in hypoxic tumors increases lung metastasis via angiopoietin-2

Por Keskin, Doruk, Kim, Jiha, Cooke, Vesselina G., Wu, Chia-Chin, Sugimoto, Hikaru, Gu, Chenghua, De Palma, Michele, Kalluri, Raghu, LeBleu, Valerie S.
Publicado no Cell Rep (2015)

Function of endogenous inhibitors of angiogenesis as endothelium-specific tumor suppressors

Por Sund, Malin, Hamano, Yuki, Sugimoto, Hikaru, Sudhakar, Akulapalli, Soubasakos, Mary, Yerramalla, Udaya, Benjamin, Laura E., Lawler, Jack, Kieran, Mark, Shah, Amish, Kalluri, Raghu
Publicado em 2005

Mice deficient in α-actinin-4 have severe glomerular disease

Por Kos, Claudine H., Le, Tu Cam, Sinha, Sumita, Henderson, Joel M., Kim, Sung Han, Sugimoto, Hikaru, Kalluri, Raghu, Gerszten, Robert E., Pollak, Martin R.
Publicado em 2003

Tet3-Mediated Hydroxymethylation of Epigenetically Silenced Genes Contributes to Bone Morphogenic Protein 7-Induced Reversal of Kidney Fibrosis

Por Tampe, Björn, Tampe, Desiree, Müller, Claudia A., Sugimoto, Hikaru, LeBleu, Valerie, Xu, Xingbo, Müller, Gerhard A., Zeisberg, Elisabeth M., Kalluri, Raghu, Zeisberg, Michael
Publicado em 2014

RhoB Loss Prevents Streptozotocin-Induced Diabetes and Ameliorates Diabetic Complications in Mice

Por Bravo-Nuevo, Arturo, Sugimoto, Hikaru, Iyer, Seema, Fallon, Zachary, Lucas, Jason M., Kazerounian, Shiva, Prendergast, George C., Kalluri, Raghu, Shapiro, Nathan I., Benjamin, Laura E.
Publicado em 2011

Identification of the NC1 Domain of α3 Chain as Critical for α3α4α5 Type IV Collagen Network Assembly

Por LeBleu, Valerie, Sund, Malin, Sugimoto, Hikaru, Birrane, Gabriel, Kanasaki, Keizo, Finan, Elizabeth, Miller, Caroline A., Gattone, Vincent H., McLaughlin, Heather, Shield, Charles F., Kalluri, Raghu
Publicado em 2010

Stem Cell Therapies Benefit Alport Syndrome

Por LeBleu, Valerie, Sugimoto, Hikaru, Mundel, Thomas M., Gerami-Naini, Behzad, Finan, Elizabeth, Miller, Caroline A., Gattone, Vincent H., Lu, Lingge, Shield, Charles F., Folkman, Judah, Kalluri, Raghu
Publicado em 2009