Stem Cell Therapies Benefit Alport Syndrome

Patients with Alport syndrome progressively lose renal function as a result of defective type IV collagen in their glomerular basement membrane. In mice lacking the α3 chain of type IV collagen (Col4A3 knockout mice), a model for Alport syndrome, transplantation of wild-type bone marrow repairs the...

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Detalles Bibliográficos
Autores principales: LeBleu, Valerie, Sugimoto, Hikaru, Mundel, Thomas M., Gerami-Naini, Behzad, Finan, Elizabeth, Miller, Caroline A., Gattone, Vincent H., Lu, Lingge, Shield, Charles F., Folkman, Judah, Kalluri, Raghu
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society of Nephrology 2009
Materias:
Basic Research
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2799182/
https://ncbi.nlm.nih.gov/pubmed/19833902
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2009010123
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