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A peek into cancer-associated fibroblasts: origins, functions and translational impact

In malignant tumors, cancer cells adapt to grow within their host tissue. As a cancer progresses, an accompanying host stromal response evolves within and around the nascent tumor. Among the host stromal constituents associated with the tumor are cancer-associated fibroblasts, a highly abundant and...

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Detalhes bibliográficos
Publicado no:Dis Model Mech
Main Authors: LeBleu, Valerie S., Kalluri, Raghu
Formato: Artigo
Idioma:Inglês
Publicado em: The Company of Biologists Ltd 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5963854/
https://ncbi.nlm.nih.gov/pubmed/29686035
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dmm.029447
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