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Blockade of PDGF receptor signaling reduces myofibroblast number and attenuates renal fibrosis

Fibrosis can be considered as wound healing that never ceases, and activated fibroblasts (myofibroblasts) probably play a critical role in this unabated tissue repair process. In the setting of renal fibrosis, two central questions remain unanswered: Where do activated myofibroblasts come from; and...

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Bibliografski detalji
Izdano u:Kidney Int
Glavni autori: LeBleu, Valerie S., Kalluri, Raghu
Format: Artigo
Jezik:Inglês
Izdano: 2011
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4316679/
https://ncbi.nlm.nih.gov/pubmed/22083636
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ki.2011.300
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