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Origin and Function of Myofibroblasts in Kidney Fibrosis

Myofibroblasts are associated with organ fibrosis but their precise origin and functional role remain unknown. We employed multiple genetically engineered mice to track, fate-map and ablate cells to determine the source and function of myofibroblasts in kidney fibrosis. Such comprehensive analysis i...

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Bibliografiske detaljer
Main Authors: LeBleu, Valerie S., Taduri, Gangadhar, O’Connell, Joyce, Teng, Yingqi, Cooke, Vesselina G., Woda, Craig, Sugimoto, Hikaru, Kalluri, Raghu
Format: Artigo
Sprog:Inglês
Udgivet: 2013
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4067127/
https://ncbi.nlm.nih.gov/pubmed/23817022
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nm.3218
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