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Origin and Function of Myofibroblasts in Kidney Fibrosis

Myofibroblasts are associated with organ fibrosis but their precise origin and functional role remain unknown. We employed multiple genetically engineered mice to track, fate-map and ablate cells to determine the source and function of myofibroblasts in kidney fibrosis. Such comprehensive analysis i...

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Main Authors: LeBleu, Valerie S., Taduri, Gangadhar, O’Connell, Joyce, Teng, Yingqi, Cooke, Vesselina G., Woda, Craig, Sugimoto, Hikaru, Kalluri, Raghu
格式: Artigo
語言:Inglês
出版: 2013
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4067127/
https://ncbi.nlm.nih.gov/pubmed/23817022
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nm.3218
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