Identification of the NC1 Domain of α3 Chain as Critical for α3α4α5 Type IV Collagen Network Assembly

The network organization of type IV collagen consisting of α3, α4, and α5 chains in the glomerular basement membrane (GBM) is speculated to involve interactions of the triple helical and NC1 domain of individual α-chains, but in vivo evidence is lacking. To specifically address the contribution of t...

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Main Authors: LeBleu, Valerie, Sund, Malin, Sugimoto, Hikaru, Birrane, Gabriel, Kanasaki, Keizo, Finan, Elizabeth, Miller, Caroline A., Gattone, Vincent H., McLaughlin, Heather, Shield, Charles F., Kalluri, Raghu
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2010
Assuntos:
Protein Structure and Folding
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3009915/
https://ncbi.nlm.nih.gov/pubmed/20847057
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.149534
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