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Bone-marrow-derived stem cells repair basement membrane collagen defects and reverse genetic kidney disease
Type IV collagen is a predominant component of basement membranes, and glomeruli of a kidney filter ≈70–90 liters of plasma every day through a specialized glomerular basement membrane (GBM). In Alport syndrome, a progressive disease primarily affecting kidneys, mutations in GBM-associated type IV c...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2006
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1464339/ https://ncbi.nlm.nih.gov/pubmed/16648256 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0601436103 |
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