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Characterization of the anti-angiogenic properties of arresten, an α1β1 integrin dependent collagen-derived tumor suppressor

Physiological and pathological turnover of basement membranes liberates biologically active cryptic molecules. Several collagen-derived fragments possess anti-angiogenic activity. Arresten is the 26-kDa non-collagenous domain of type IV collagen α1 chain. It functions as an efficient inhibitor of an...

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Bibliographic Details
Main Authors: Nyberg, Pia, Xie, Liang, Sugimoto, Hikaru, Colorado, Pablo, Sund, Malin, Holthaus, Kathryn, Sudhakar, Akulapalli, Salo, Tuula, Kalluri, Raghu
Format: Artigo
Language:Inglês
Published: 2008
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2613512/
https://ncbi.nlm.nih.gov/pubmed/18775695
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yexcr.2008.08.011
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