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Identification of Epithelial to Mesenchymal Transition as a Novel Source of Fibroblasts in Intestinal Fibrosis

Intestinal fibrosis is a major complication of Crohn disease (CD), but the precise mechanism by which it occurs is incompletely understood. As a result, specific therapies to halt or even reverse fibrosis have not been explored. Here, we evaluated the contribution of epithelial to mesenchymal transi...

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Detalhes bibliográficos
Principais autores: Flier, Sarah N., Tanjore, Harikrishna, Kokkotou, Efi G., Sugimoto, Hikaru, Zeisberg, Michael, Kalluri, Raghu
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2010
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2888433/
https://ncbi.nlm.nih.gov/pubmed/20363741
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.102012
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