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Fibroblasts in Kidney Fibrosis Emerge via Endothelial-to-Mesenchymal Transition

Fibroblasts are key mediators of fibrosis in the kidney and other organs, but their origin during fibrosis is still not completely clear. Activated fibroblasts likely arise from resident quiescent fibroblasts via epithelial-to-mesenchymal transition and from the bone marrow. Here, we demonstrate tha...

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Bibliografiske detaljer
Main Authors: Zeisberg, Elisabeth M., Potenta, Scott E., Sugimoto, Hikaru, Zeisberg, Michael, Kalluri, Raghu
Format: Artigo
Sprog:Inglês
Udgivet: American Society of Nephrology 2008
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2588112/
https://ncbi.nlm.nih.gov/pubmed/18987304
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2008050513
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