Fibroblasts in Kidney Fibrosis Emerge via Endothelial-to-Mesenchymal Transition

Fibroblasts are key mediators of fibrosis in the kidney and other organs, but their origin during fibrosis is still not completely clear. Activated fibroblasts likely arise from resident quiescent fibroblasts via epithelial-to-mesenchymal transition and from the bone marrow. Here, we demonstrate tha...

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Bibliographic Details
Main Authors: Zeisberg, Elisabeth M., Potenta, Scott E., Sugimoto, Hikaru, Zeisberg, Michael, Kalluri, Raghu
Format: Artigo
Language:Inglês
Published: American Society of Nephrology 2008
Subjects:
Brief Communications
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2588112/
https://ncbi.nlm.nih.gov/pubmed/18987304
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2008050513
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