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Epithelial to Mesenchymal Transition induces cell cycle arrest and parenchymal damage in renal fibrosis
Kidney fibrosis is marked by an epithelial–to–mesenchymal transition (EMT) by tubular epithelial cells (TECs). Here we find that during renal fibrosis TECs acquire a partial EMT program during which they remain associated with their basement membrane and express markers of both epithelial and mesenc...
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| Udgivet i: | Nat Med |
|---|---|
| Main Authors: | , , , , , , , , , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2015
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4587560/ https://ncbi.nlm.nih.gov/pubmed/26236991 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nm.3902 |
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