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Dual reporter genetic mouse models of pancreatic cancer identify an epithelial‐to‐mesenchymal transition‐independent metastasis program

Epithelial‐to‐mesenchymal transition (EMT) is a recognized eukaryotic cell differentiation program that is also observed in association with invasive tumors. Partial EMT program in carcinomas imparts cancer cells with mesenchymal‐like features and is proposed as essential for metastasis. Precise det...

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Bibliografiske detaljer
Udgivet i:EMBO Mol Med
Main Authors: Chen, Yang, LeBleu, Valerie S, Carstens, Julienne L, Sugimoto, Hikaru, Zheng, Xiaofeng, Malasi, Shruti, Saur, Dieter, Kalluri, Raghu
Format: Artigo
Sprog:Inglês
Udgivet: John Wiley and Sons Inc. 2018
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6180301/
https://ncbi.nlm.nih.gov/pubmed/30120146
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/emmm.201809085
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