Dual reporter genetic mouse models of pancreatic cancer identify an epithelial‐to‐mesenchymal transition‐independent metastasis program

Epithelial‐to‐mesenchymal transition (EMT) is a recognized eukaryotic cell differentiation program that is also observed in association with invasive tumors. Partial EMT program in carcinomas imparts cancer cells with mesenchymal‐like features and is proposed as essential for metastasis. Precise det...

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Vydáno v:EMBO Mol Med
Hlavní autoři: Chen, Yang, LeBleu, Valerie S, Carstens, Julienne L, Sugimoto, Hikaru, Zheng, Xiaofeng, Malasi, Shruti, Saur, Dieter, Kalluri, Raghu
Médium: Artigo
Jazyk:Inglês
Vydáno: John Wiley and Sons Inc. 2018
Témata:
Research Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6180301/
https://ncbi.nlm.nih.gov/pubmed/30120146
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/emmm.201809085
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