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Microenvironment-dependent cues trigger miRNA-regulated feedback loop to facilitate the EMT/MET switch

The metastatic spread of tumor epithelial cells accounts for over 90% of cancer-specific mortality; however, the molecular mechanisms that govern tumor spread and distant recolonization remain unclear. In this issue of JCI, Rokavec and colleagues shine light on this murky aspect of tumor biology by...

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Detalhes bibliográficos
Main Authors: Carstens, Julienne L., Lovisa, Sara, Kalluri, Raghu
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3973103/
https://ncbi.nlm.nih.gov/pubmed/24642461
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI75239
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