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Targeting vascular pericytes in hypoxic tumors increases lung metastasis via angiopoietin-2
Strategies to target angiogenesis include inhibition of the vessel-stabilizing properties of vascular pericytes. Pericyte depletion in early-stage non-hypoxic tumors suppressed nascent angiogenesis, tumor growth and lung metastasis. In contrast, pericyte depletion in advanced-stage hypoxic tumors wi...
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| Publié dans: | Cell Rep |
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| Auteurs principaux: | , , , , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2015
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4342328/ https://ncbi.nlm.nih.gov/pubmed/25704811 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2015.01.035 |
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