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Podoplanin(+) tumor lymphatics are rate limiting for breast cancer metastasis

Metastatic dissemination employs both the blood and lymphatic vascular systems. Solid tumors dynamically remodel and generate both vessel types during cancer progression. Lymphatic vessel invasion and cancer cells in the tumor-draining lymph nodes (LNs) are prognostic markers for breast cancer metas...

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Detalhes bibliográficos
Publicado no:PLoS Biol
Main Authors: Chen, Yang, Keskin, Doruk, Sugimoto, Hikaru, Kanasaki, Keizo, Phillips, Patricia E., Bizarro, Lauren, Sharpe, Arlene, LeBleu, Valerie S., Kalluri, Raghu
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6310240/
https://ncbi.nlm.nih.gov/pubmed/30592710
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.2005907
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