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Deletion of Smad4 in Fibroblasts Leads to Defective Chondrocyte Maturation and Cartilage Production in a TGF Type II Receptor Independent Manner

The transforming growth factor β (TGFβ) superfamily growth factors play vital roles during the development, homeostasis, and pathogenesis of multi-cellular organisms. Smad4 serves as an exclusive co-activating smad that elicits most of the transcription responses invoked by the TGFβ superfamily memb...

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Bibliografski detalji
Glavni autori: Teng, Yingqi, Kanasaki, Keizo, Bardeesy, Nabeel, Sugimoto, Hikaru, Kalluri, Raghu
Format: Artigo
Jezik:Inglês
Izdano: 2011
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3999521/
https://ncbi.nlm.nih.gov/pubmed/21376704
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2011.02.142
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