TGF-β/Smad3 Signals Repress Chondrocyte Hypertrophic Differentiation and Are Required for Maintaining Articular Cartilage

Endochondral ossification begins from the condensation and differentiation of mesenchymal cells into cartilage. The cartilage then goes through a program of cell proliferation, hypertrophic differentiation, calcification, apoptosis, and eventually is replaced by bone. Unlike most cartilage, articula...

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Bibliografiske detaljer
Main Authors: Yang, Xiao, Chen, Lin, Xu, Xiaoling, Li, Cuiling, Huang, Cuifen, Deng, Chu-Xia
Format: Artigo
Sprog:Inglês
Udgivet: The Rockefeller University Press 2001
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Original Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2185521/
https://ncbi.nlm.nih.gov/pubmed/11285272
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