Rapid in vivo validation of candidate drivers derived from the PTEN-mutant prostate metastasis genome

Por Cho, Hyejin, Stahlhut, Carlos, Herzka, Tali, Watrud, Kaitlin, Robinson, Brian D., Trotman, Lloyd C.
Publicado no Methods (2015)

Mutations in p53 change phosphatidylinositol acyl chain composition

Por Naguib, Adam, Bencze, Gyula, Engle, Dannielle, Chio, Iok I. C., Herzka, Tali, Watrud, Kaitlin, Bencze, Szilvia, Tuveson, David A., Pappin, Darryl J, Trotman, Lloyd C.
Publicado no Cell Rep (2014)

RapidCaP, a novel GEM model for analysis and therapy of metastatic prostate cancer reveals Myc as a driver of Pten-mutant metastasis

Por Cho, Hyejin, Herzka, Tali, Zheng, Wu, Qi, Jun, Wilkinson, John E., Bradner, James E., Robinson, Brian D., Castillo-Martin, Mireia, Cordon-Cardo, Carlos, Trotman, Lloyd C.
Publicado em 2014

Mitochondrial Complex I Inhibitors Expose a Vulnerability for Selective Killing of Pten-Null Cells

Por Naguib, Adam, Mathew, Grinu, Reczek, Colleen R., Watrud, Kaitlin, Ambrico, Alexandra, Herzka, Tali, Salas, Irene Casanova, Lee, Matthew F., El-Amine, Nour, Zheng, Wu, Di Francesco, M. Emilia, Marszalek, Joseph R., Pappin, Darryl J., Chandel, Navdeep S., Trotman, Lloyd C.
Publicado no Cell Rep (2018)

Myc drives Pten/p53-deficient proliferation and metastasis due to Il6-secretion and Akt-suppression via Phlpp2

Por Nowak, Dawid G., Cho, Hyejin, Herzka, Tali, Watrud, Kaitlin, DeMarco, Daniel V., Wang, Victoria M. Y., Senturk, Serif, Fellmann, Christof, Ding, David, Beinortas, Tumas, Kleinman, David, Chen, Muhan, Sordella, Raffaella, Wilkinson, John E., Castillo-Martin, Mireia, Cordon-Cardo, Carlos, Robinson, Brian D., Trotman, Lloyd C.
Publicado no Cancer Discov (2015)

The nuclear transport receptor Importin-11 is a tumor suppressor that maintains PTEN protein

Por Chen, Muhan, Nowak, Dawid G., Narula, Navneet, Robinson, Brian, Watrud, Kaitlin, Ambrico, Alexandra, Herzka, Tali M., Zeeman, Martha E., Minderer, Matthias, Zheng, Wu, Ebbesen, Saya H., Plafker, Kendra S., Stahlhut, Carlos, Wang, Victoria M.Y., Wills, Lorna, Nasar, Abu, Castillo-Martin, Mireia, Cordon-Cardo, Carlos, Wilkinson, John E., Powers, Scott, Sordella, Raffaella, Altorki, Nasser K., Mittal, Vivek, Stiles, Brendon M., Plafker, Scott M., Trotman, Lloyd C.
Publicado no J Cell Biol (2017)