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Rapid in vivo validation of candidate drivers derived from the PTEN-mutant prostate metastasis genome
Human genome analyses have revealed that increasing gene copy number alteration is a driving force of incurable prostate cancer (PC). Since most of the affected genes are hidden within large amplifications or deletions, there is a need for fast and faithful validation of drivers. However, classic ge...
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Publicado no: | Methods |
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Main Authors: | , , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2015
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4429512/ https://ncbi.nlm.nih.gov/pubmed/25592467 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ymeth.2014.12.022 |
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