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Rapid in vivo validation of candidate drivers derived from the PTEN-mutant prostate metastasis genome

Human genome analyses have revealed that increasing gene copy number alteration is a driving force of incurable prostate cancer (PC). Since most of the affected genes are hidden within large amplifications or deletions, there is a need for fast and faithful validation of drivers. However, classic ge...

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Detalhes bibliográficos
Publicado no:Methods
Main Authors: Cho, Hyejin, Stahlhut, Carlos, Herzka, Tali, Watrud, Kaitlin, Robinson, Brian D., Trotman, Lloyd C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4429512/
https://ncbi.nlm.nih.gov/pubmed/25592467
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ymeth.2014.12.022
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