Stereoselective Synthesis of the Disaccharide Unit of Incednine

por Abbott, Jason R., Roush, William R.
Publicado 2012

Stereoselective Synthesis of a Model C(18)–C(35) Spiroketal Fragment of Integramycin

por Sun, Huikai, Abbott, Jason R., Roush, William R.
Publicado 2011

High-throughput screening identifies small molecules that bind to the RAS:SOS:RAS complex and perturb RAS signaling

por Burns, Michael C., Howes, Jennifer E., Sun, Qi, Little, Andrew J., Camper, DeMarco V., Abbott, Jason R., Phan, Jason, Lee, Taekyu, Waterson, Alex G., Rossanese, Olivia W., Fesik, Stephen W.
Publicado en Anal Biochem (2018)

Discovery of Quinazolines That Activate SOS1-Mediated Nucleotide Exchange on RAS

por Abbott, Jason R., Patel, Pratiq A., Howes, Jennifer E., Akan, Denis T., Kennedy, J. Phillip, Burns, Michael C., Browning, Carrie F., Sun, Qi, Rossanese, Olivia W., Phan, Jason, Waterson, Alex G., Fesik, Stephen W.
Publicado en ACS Med Chem Lett (2018)

Discovery and Structure-Based Optimization of Benzimidazole-Derived Activators of SOS1-Mediated Nucleotide Exchange on RAS

por Hodges, Timothy R., Abbott, Jason R., Little, Andrew J., Sarkar, Dhruba, Salovich, James M., Howes, Jennifer E., Akan, Denis T., Sai, Jiqing, Arnold, Allison L., Browning, Carrie, Burns, Michael C., Sobolik, Tammy, Sun, Qi, Beesetty, Yugandhar, Coker, Jesse A., Scharn, Dirk, Stadtmueller, Heinz, Rossanese, Olivia W., Phan, Jason, Waterson, Alex G., McConnell, Darryl B., Fesik, Stephen W.
Publicado en J Med Chem (2018)