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Stereoselective Synthesis of a Model C(18)–C(35) Spiroketal Fragment of Integramycin

[Image: see text] A highly stereoselective synthesis of a model C(18)–C(35) spiroketal unit (7) of integramycin has been accomplished via an enantioselective stannyl-crotylboration reaction and an N-iodosuccinimide-mediated spiroketalization of 19a.

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Détails bibliographiques
Auteurs principaux: Sun, Huikai, Abbott, Jason R., Roush, William R.
Format: Artigo
Langue:Inglês
Publié: 2011
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3094501/
https://ncbi.nlm.nih.gov/pubmed/21510632
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ol200834p
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