Norbenzomorphan Framework as a Novel Scaffold for Generating Sigma 2 Receptor/PGRMC1 Subtype Selective Ligands

Por Sahn, James J., Hodges, Timothy R., Chan, Jessica Z., Martin, Stephen F.
Publicado no ChemMedChem (2016)

Norbenzomorphan Scaffold: Chemical Tool for Modulating Sigma Receptor-Subtype Selectivity

Por Sahn, James J., Hodges, Timothy R., Chan, Jessica Z., Martin, Stephen F.
Publicado no ACS Med Chem Lett (2017)

High-Content Microfluidic Screening Platform Used To Identify σ2R/Tmem97 Binding Ligands that Reduce Age-Dependent Neurodegeneration in C. elegans SC_APP Model

Por Monda, Sudip, Hegarty, Evan, Sahn, James J., Scott, Luisa L., Gökçe, Sertan Kutal, Martin, Chris, Ghorashian, Navid, Satarasinghe, Praveen Navoda, Iyer, Sangeetha, Sae-Lee, Wisath, Hodges, Timothy R., Pierce, Jonathan T., Martin, Stephen F., Ben-Yakar, Adela
Publicado no ACS Chem Neurosci (2018)

Small molecule modulators of σ2R/Tmem97 reduce alcohol withdrawal-induced behaviors

Por Scott, Luisa L., Sahn, James J., Ferragud, Antonio, Yen, Rachel C., Satarasinghe, Praveen N., Wood, Michael D., Hodges, Timothy R., Shi, Ted, Prakash, Brooke A., Friese, Kaitlyn M., Shen, Angela, Sabino, Valentina, Pierce, Jonathan T., Martin, Stephen F.
Publicado no Neuropsychopharmacology (2018)

Neuroprotective Efficacy of a Sigma 2 Receptor/TMEM97 Modulator (DKR-1677) after Traumatic Brain Injury

Por Vázquez-Rosa, Edwin, Watson, Michael R., Sahn, James J., Hodges, Timothy R., Schroeder, Rachel E., Cintrón-Pérez, Coral J., Shin, Min-Kyoo, Yin, Terry C., Emery, Josie L., Martin, Stephen F., Liebl, Daniel J., Pieper, Andrew A.
Publicado no ACS Chem Neurosci (2018)