Small molecule modulators of σ2R/Tmem97 reduce alcohol withdrawal-induced behaviors

Repeated cycles of intoxication and withdrawal enhance the negative reinforcing properties of alcohol and lead to neuroadaptations that underlie withdrawal symptoms driving alcohol dependence. Pharmacotherapies that target these neuroadaptations may help break the cycle of dependence. The sigma-1 re...

Celý popis

Uloženo v:
Podrobná bibliografie
Vydáno v:Neuropsychopharmacology
Hlavní autoři: Scott, Luisa L., Sahn, James J., Ferragud, Antonio, Yen, Rachel C., Satarasinghe, Praveen N., Wood, Michael D., Hodges, Timothy R., Shi, Ted, Prakash, Brooke A., Friese, Kaitlyn M., Shen, Angela, Sabino, Valentina, Pierce, Jonathan T., Martin, Stephen F.
Médium: Artigo
Jazyk:Inglês
Vydáno: Springer International Publishing 2018
Témata:
Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6046036/
https://ncbi.nlm.nih.gov/pubmed/29728649
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41386-018-0067-z
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky