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Small molecule modulators of σ2R/Tmem97 reduce alcohol withdrawal-induced behaviors
Repeated cycles of intoxication and withdrawal enhance the negative reinforcing properties of alcohol and lead to neuroadaptations that underlie withdrawal symptoms driving alcohol dependence. Pharmacotherapies that target these neuroadaptations may help break the cycle of dependence. The sigma-1 re...
Gardado en:
| Publicado en: | Neuropsychopharmacology |
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| Main Authors: | , , , , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Springer International Publishing
2018
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6046036/ https://ncbi.nlm.nih.gov/pubmed/29728649 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41386-018-0067-z |
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