Neuroprotective Efficacy of a Sigma 2 Receptor/TMEM97 Modulator (DKR-1677) after Traumatic Brain Injury

Compounds targeting the sigma 2 receptor, which we recently cloned and showed to be identical with transmembrane protein 97 (σ2R/TMEM97), are broadly applicable therapeutic agents currently in clinical trials for imaging in breast cancer and for treatment of Alzheimer’s disease and schizophrenia. Th...

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Vydáno v:ACS Chem Neurosci
Hlavní autoři: Vázquez-Rosa, Edwin, Watson, Michael R., Sahn, James J., Hodges, Timothy R., Schroeder, Rachel E., Cintrón-Pérez, Coral J., Shin, Min-Kyoo, Yin, Terry C., Emery, Josie L., Martin, Stephen F., Liebl, Daniel J., Pieper, Andrew A.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2018
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6862717/
https://ncbi.nlm.nih.gov/pubmed/30421909
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acschemneuro.8b00543
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