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Sigma-2 receptor/TMEM97 agonist PB221 as an alternative drug for brain tumor

Abstract Background There are limited effective drugs that can reach the brain to target brain tumors, in particular glioblastoma, which is one of the most difficult cancers to be cured from. Because the overexpression of the sigma-2 receptor is frequently reported in glioma clinical samples and ass...

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Detalhes bibliográficos
Main Authors: Chia-Chi Liu, Ching-Fang Yu, Shu-Chi Wang, Hsueh-Yin Li, Chiu-Min Lin, Hsia-Han Wang, Carmen Abate, Chi-Shiun Chiang
Formato: Artigo
Idioma:Inglês
Publicado em: BMC 2019-05-01
Colecção:BMC Cancer
Acesso em linha:http://link.springer.com/article/10.1186/s12885-019-5700-7
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