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Sigma 2 Receptor/Tmem97 Agonists Produce Long Lasting Antineuropathic Pain Effects in Mice

Neuropathic pain is an important medical problem with few effective treatments. The sigma 1 receptor (σ1R) is known to be a potential target for neuropathic pain therapeutics, and antagonists for this receptor are effective in preclinical models and are currently in phase II clinical trials. Convers...

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Pubblicato in:ACS Chem Neurosci
Autori principali: Sahn, James J., Mejia, Galo L., Ray, Pradipta R., Martin, Stephen F., Price, Theodore J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2017
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5715471/
https://ncbi.nlm.nih.gov/pubmed/28644012
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acschemneuro.7b00200
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