VU0477573: Partial Negative Allosteric Modulator of the Subtype 5 Metabotropic Glutamate Receptor with In Vivo Efficacy

著者: Nickols, Hilary Highfield, Yuh, Joannes P., Gregory, Karen J., Morrison, Ryan D., Bates, Brittney S., Stauffer, Shaun R., Emmitte, Kyle A., Bubser, Michael, Peng, Weimin, Nedelcovych, Michael T., Thompson, Analisa, Lv, Xiaohui, Xiang, Zixiu, Daniels, J. Scott, Niswender, Colleen M., Lindsley, Craig W., Jones, Carrie K., Conn, P. Jeffrey
出版年 J Pharmacol Exp Ther (2016)

Discovery of Potent 2-Aryl-6,7-Dihydro-5H-Pyrrolo[1,2-a]imidazoles as WDR5 WIN-site Inhibitors Using Fragment-Based Methods and Structure-Based Design

著者: Wang, Feng, Jeon, Kyu Ok, Salovich, James M., Macdonald, Jonathan D., Alvarado, Joseph, Gogliotti, Rocco D., Phan, Jason, Olejniczak, Edward T., Sun, Qi, Wang, Shidong, Camper, DeMarco, Yuh, Joannes P., Shaw, J. Grace, Sai, Jiqing, Rossanese, Olivia W., Tansey, William P., Stauffer, Shaun R., Fesik, Stephen W.
出版年 J Med Chem (2018)

Discovery and Optimization of Salicylic Acid-Derived Sulfonamide Inhibitors of the WD Repeat-Containing Protein 5 (WDR5)–MYC Protein–Protein Interaction

著者: Macdonald, Jonathan D., Simon, Selena Chacón, Han, Changho, Wang, Feng, Shaw, J. Grace, Howes, Jennifer E., Sai, Jiqing, Yuh, Joannes P., Camper, Demarco, Alicie, Bethany M., Alvarado, Joseph, Nikhar, Sameer, Payne, William, Aho, Erin R., Bauer, Joshua A., Zhao, Bin, Phan, Jason, Thomas, Lance R., Rossanese, Olivia W., Tansey, William P., Waterson, Alex G., Stauffer, Shaun R., Fesik, Stephen W.
出版年 J Med Chem (2019)