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DNA replication stress mediates APOBEC3 family mutagenesis in breast cancer
BACKGROUND: The APOBEC3 family of cytidine deaminases mutate the cancer genome in a range of cancer types. Although many studies have documented the downstream effects of APOBEC3 activity through next-generation sequencing, less is known about their upstream regulation. In this study, we sought to i...
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| Publicat a: | Genome Biol |
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| Autors principals: | , , , , , , , , , , , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
BioMed Central
2016
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5025597/ https://ncbi.nlm.nih.gov/pubmed/27634334 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13059-016-1042-9 |
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