A high-throughput fluorescence polarization anisotropy assay for the 70N domain of Replication Protein A

Replication Protein A (RPA) interacts with multiple checkpoint proteins and promotes signaling through the ATR kinase, a key regulator of checkpoint pathways in the mammalian response to DNA damage. In cancer cells, increased DNA repair activity contributes to resistance to chemotherapy. Therefore,...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Souza-Fagundes, Elaine M., Frank, Andreas O., Feldkamp, Michael D., Dorset, Daniel C., Chazin, Walter J., Rossanese, Olivia W., Olejniczak, Edward T., Fesik, Stephen W.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3274598/
https://ncbi.nlm.nih.gov/pubmed/22197419
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ab.2011.11.025
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados