טוען...
A High-throughput Fluorescence Polarization Assay for Inhibitors of Gyrase B
DNA gyrase, a type II topoisomerase that introduces negative supercoils into DNA, is a validated antibacterial drug target. The holoenzyme is composed of 2 subunits, gyrase A (GyrA) and gyrase B (GyrB), which form a functional A(2)B(2) heterotetramer required for bacterial viability. A novel fluores...
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| Main Authors: | , , , , , , , , |
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| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
2011
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3176662/ https://ncbi.nlm.nih.gov/pubmed/21245469 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1087057110392038 |
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