Cdc1p Is an Endoplasmic Reticulum-Localized Putative Lipid Phosphatase That Affects Golgi Inheritance and Actin Polarization by Activating Ca(2+) Signaling

af Losev, Eugene, Papanikou, Effrosyni, Rossanese, Olivia W., Glick, Benjamin S.
Udgivet 2008

Golgi Structure Correlates with Transitional Endoplasmic Reticulum Organization in Pichia pastoris and Saccharomyces cerevisiae

af Rossanese, Olivia W., Soderholm, Jon, Bevis, Brooke J., Sears, Irina B., O'Connor, James, Williamson, Edward K., Glick, Benjamin S.
Udgivet 1999

A Role for Actin, Cdc1p, and Myo2p in the Inheritance of Late Golgi Elements in Saccharomyces cerevisiae

af Rossanese, Olivia W., Reinke, Catherine A., Bevis, Brooke J., Hammond, Adam T., Sears, Irina B., O'Connor, James, Glick, Benjamin S.
Udgivet 2001

Discovery of Small Molecules that Bind to K-Ras and Inhibit Sos-mediated Activation

af Sun, Qi, Burke, Jason P., Phan, Jason, Burns, Michael C., Olejniczak, Edward T., Waterson, Alex G., Lee, Taekyu, Rossanese, Olivia W., Fesik, Stephen W.
Udgivet 2012

A high-throughput fluorescence polarization anisotropy assay for the 70N domain of Replication Protein A

af Souza-Fagundes, Elaine M., Frank, Andreas O., Feldkamp, Michael D., Dorset, Daniel C., Chazin, Walter J., Rossanese, Olivia W., Olejniczak, Edward T., Fesik, Stephen W.
Udgivet 2011

A Yeast t-SNARE Involved in Endocytosis

af Séron, Karin, Tieaho, Ville, Prescianotto-Baschong, Cristina, Aust, Thomas, Blondel, Marie-Odile, Guillaud, Philippe, Devilliers, Ginette, Rossanese, Olivia W., Glick, Benjamin S., Riezman, Howard, Keränen, Sirkka, Haguenauer-Tsapis, Rosine
Udgivet 1998

Discovery of Protein–Protein Interaction Inhibitors of Replication Protein A

af Patrone, James D., Kennedy, J. Phillip, Frank, Andreas O., Feldkamp, Michael D., Vangamudi, Bhavatarini, Pelz, Nicholas F., Rossanese, Olivia W., Waterson, Alex G., Chazin, Walter J., Fesik, Stephen W.
Udgivet 2013

Golgi enlargement in Arf-depleted yeast cells is due to altered dynamics of cisternal maturation

af Bhave, Madhura, Papanikou, Effrosyni, Iyer, Prasanna, Pandya, Koushal, Jain, Bhawik Kumar, Ganguly, Abira, Sharma, Chandrakala, Pawar, Ketakee, Austin, Jotham, Day, Kasey J., Rossanese, Olivia W., Glick, Benjamin S., Bhattacharyya, Dibyendu
Udgivet 2014

Approach for targeting Ras with small molecules that activate SOS-mediated nucleotide exchange

af Burns, Michael C., Sun, Qi, Daniels, R. Nathan, Camper, DeMarco, Kennedy, J. Phillip, Phan, Jason, Olejniczak, Edward T., Lee, Taekyu, Waterson, Alex G., Rossanese, Olivia W., Fesik, Stephen W.
Udgivet 2014

Discovery of a Potent Stapled Helix Peptide That Binds to the 70N Domain of Replication Protein A

af Frank, Andreas O., Vangamudi, Bhavatarini, Feldkamp, Michael D., Souza-Fagundes, Elaine M., Luzwick, Jessica W., Cortez, David, Olejniczak, Edward T., Waterson, Alex G., Rossanese, Olivia W., Chazin, Walter J., Fesik, Stephen W.
Udgivet 2014

High-throughput screening identifies small molecules that bind to the RAS:SOS:RAS complex and perturb RAS signaling

af Burns, Michael C., Howes, Jennifer E., Sun, Qi, Little, Andrew J., Camper, DeMarco V., Abbott, Jason R., Phan, Jason, Lee, Taekyu, Waterson, Alex G., Rossanese, Olivia W., Fesik, Stephen W.
Udgivet i Anal Biochem (2018)

Discovery of a Potent Inhibitor of Replication Protein A Protein-Protein Interactions Using a Fragment Linking Approach

af Frank, Andreas O., Feldkamp, Michael D., Kennedy, J. Phillip, Waterson, Alex G., Pelz, Nicholas F., Patrone, James D., Vangamudi, Bhavatarini, Camper, DeMarco V., Rossanese, Olivia W., Chazin, Walter J., Fesik, Stephen W.
Udgivet 2013

Diphenylpyrazoles as Replication Protein A Inhibitors

af Waterson, Alex G., Kennedy, J. Phillip, Patrone, James D., Pelz, Nicholas F., Feldkamp, Michael D., Frank, Andreas O., Vangamudi, Bhavatarini, Souza-Fagundes, Elaine M., Rossanese, Olivia W., Chazin, Walter J., Fesik, Stephen W.
Udgivet i ACS Med Chem Lett (2014)

Discovery of Quinazolines That Activate SOS1-Mediated Nucleotide Exchange on RAS

af Abbott, Jason R., Patel, Pratiq A., Howes, Jennifer E., Akan, Denis T., Kennedy, J. Phillip, Burns, Michael C., Browning, Carrie F., Sun, Qi, Rossanese, Olivia W., Phan, Jason, Waterson, Alex G., Fesik, Stephen W.
Udgivet i ACS Med Chem Lett (2018)

Discovery of Tricyclic Indoles That Potently Inhibit Mcl-1 Using Fragment-Based Methods and Structure-Based Design

af Burke, Jason P., Bian, Zhiguo, Shaw, Subrata, Zhao, Bin, Goodwin, Craig M., Belmar, Johannes, Browning, Carrie F., Vigil, Dominico, Friberg, Anders, Camper, DeMarco V., Rossanese, Olivia W., Lee, Taekyu, Olejniczak, Edward T., Fesik, Stephen W.
Udgivet i J Med Chem (2015)

DNA replication stress mediates APOBEC3 family mutagenesis in breast cancer

af Kanu, Nnennaya, Cerone, Maria Antonietta, Goh, Gerald, Zalmas, Lykourgos-Panagiotis, Bartkova, Jirina, Dietzen, Michelle, McGranahan, Nicholas, Rogers, Rebecca, Law, Emily K., Gromova, Irina, Kschischo, Maik, Walton, Michael I., Rossanese, Olivia W., Bartek, Jiri, Harris, Reuben S., Venkatesan, Subramanian, Swanton, Charles
Udgivet i Genome Biol (2016)

Discovery of 2-Indole-acylsulfonamide Myeloid Cell Leukemia 1 (Mcl-1) Inhibitors Using Fragment-Based Methods

af Pelz, Nicholas F., Bian, Zhiguo, Zhao, Bin, Shaw, Subrata, Tarr, James C., Belmar, Johannes, Gregg, Claire, Camper, DeMarco V., Goodwin, Craig M., Arnold, Allison L., Sensintaffar, John L., Friberg, Anders, Rossanese, Olivia W., Lee, Taekyu, Olejniczak, Edward T., Fesik, Stephen W.
Udgivet i J Med Chem (2016)

Identification and Optimization of Anthranilic Acid-Based Inhibitors of Replication Protein A

af Patrone, James D., Pelz, Nicholas F., Bates, Brittney S., Souza-Fagundes, Elaine M., Vangamudi, Bhavatarini, Camper, Demarco V., Kuznetsov, Alexey G., Browning, Carrie F., Feldkamp, Michael D., Frank, Andreas O., Gilston, Benjamin A., Olejniczak, Edward T., Rossanese, Olivia W., Waterson, Alex G., Chazin, Walter J., Fesik, Stephen W.
Udgivet i ChemMedChem (2016)

Discovery of Potent 2-Aryl-6,7-Dihydro-5H-Pyrrolo[1,2-a]imidazoles as WDR5 WIN-site Inhibitors Using Fragment-Based Methods and Structure-Based Design

af Wang, Feng, Jeon, Kyu Ok, Salovich, James M., Macdonald, Jonathan D., Alvarado, Joseph, Gogliotti, Rocco D., Phan, Jason, Olejniczak, Edward T., Sun, Qi, Wang, Shidong, Camper, DeMarco, Yuh, Joannes P., Shaw, J. Grace, Sai, Jiqing, Rossanese, Olivia W., Tansey, William P., Stauffer, Shaun R., Fesik, Stephen W.
Udgivet i J Med Chem (2018)

Discovery of Dabrafenib: A Selective Inhibitor of Raf Kinases with Antitumor Activity against B-Raf-Driven Tumors

af Rheault, Tara R., Stellwagen, John C., Adjabeng, George M., Hornberger, Keith R., Petrov, Kimberly G., Waterson, Alex G., Dickerson, Scott H., Mook, Robert A., Laquerre, Sylvie G., King, Alastair J., Rossanese, Olivia W., Arnone, Marc R., Smitheman, Kimberly N., Kane-Carson, Laurie S., Han, Chao, Moorthy, Ganesh S., Moss, Katherine G., Uehling, David E.
Udgivet 2013