Crystal structure of the Yersinia type III secretion protein YscE

द्वारा Phan, Jason, Austin, Brian P., Waugh, David S.
प्रकाशित 2005

Erosion of Embolization Coils into the Renal Collecting System Mimicking Stone

द्वारा Phan, Jason, Lall, Chandana, Moskowitz, Ross, Clayman, Ralph, Landman, Jaime
प्रकाशित 2012

Fragment-Based Screening of the Bromodomain of ATAD2

द्वारा Harner, Mary J., Chauder, Brian A., Phan, Jason, Fesik, Stephen W.
में प्रकाशित J Med Chem (2014)

Physical Therapy for Gait, Balance, and Cognition in Individuals with Cognitive Impairment: A Retrospective Analysis

द्वारा Longhurst, Jason, Phan, Jason, Chen, Elbert, Jackson, Steven, Landers, Merrill R.
में प्रकाशित Rehabil Res Pract (2020)

Structure-based Design of High Affinity Peptides Inhibiting the Interaction of p53 with MDM2 and MDMX

द्वारा Phan, Jason, Li, Zhenyu, Kasprzak, Agnieszka, Li, Baozong, Sebti, Said, Guida, Wayne, Schönbrunn, Ernst, Chen, Jiandong
प्रकाशित 2010

A method for the second-site screening of K-Ras in the presence of a covalently attached first-site ligand

द्वारा Sun, Qi, Phan, Jason, Friberg, Anders R., Camper, DeMarco V., Olejniczak, Edward T., Fesik, Stephen W.
में प्रकाशित J Biomol NMR (2014)

Heterologous desensitization of cardiac β-adrenergic signal via hormone-induced βAR/arrestin/PDE4 complexes

द्वारा Shi, Qian, Li, Minghui, Mika, Delphine, Fu, Qin, Kim, Sungjin, Phan, Jason, Shen, Ao, Vandecasteele, Gregoire, Xiang, Yang K.
में प्रकाशित Cardiovasc Res (2017)

Discovery of Small Molecules that Bind to K-Ras and Inhibit Sos-mediated Activation

द्वारा Sun, Qi, Burke, Jason P., Phan, Jason, Burns, Michael C., Olejniczak, Edward T., Waterson, Alex G., Lee, Taekyu, Rossanese, Olivia W., Fesik, Stephen W.
प्रकाशित 2012

Approach for targeting Ras with small molecules that activate SOS-mediated nucleotide exchange

द्वारा Burns, Michael C., Sun, Qi, Daniels, R. Nathan, Camper, DeMarco, Kennedy, J. Phillip, Phan, Jason, Olejniczak, Edward T., Lee, Taekyu, Waterson, Alex G., Rossanese, Olivia W., Fesik, Stephen W.
प्रकाशित 2014

High-throughput screening identifies small molecules that bind to the RAS:SOS:RAS complex and perturb RAS signaling

द्वारा Burns, Michael C., Howes, Jennifer E., Sun, Qi, Little, Andrew J., Camper, DeMarco V., Abbott, Jason R., Phan, Jason, Lee, Taekyu, Waterson, Alex G., Rossanese, Olivia W., Fesik, Stephen W.
में प्रकाशित Anal Biochem (2018)

Discovery of Quinazolines That Activate SOS1-Mediated Nucleotide Exchange on RAS

द्वारा Abbott, Jason R., Patel, Pratiq A., Howes, Jennifer E., Akan, Denis T., Kennedy, J. Phillip, Burns, Michael C., Browning, Carrie F., Sun, Qi, Rossanese, Olivia W., Phan, Jason, Waterson, Alex G., Fesik, Stephen W.
में प्रकाशित ACS Med Chem Lett (2018)

Discovery of WD Repeat-Containing Protein 5 (WDR5)-MYC inhibitors using fragment-based methods and structure-based design

द्वारा Chacón Simon, Selena, Wang, Feng, Thomas, Lance R., Phan, Jason, Zhao, Bin, Olejniczak, Edward T., Macdonald, Jonathan D., Shaw, J. Grace, Schlund, Caden, Payne, William, Creighton, Joy, Stauffer, Shaun R., Waterson, Alex G., Tansey, William P., Fesik, Stephen W.
में प्रकाशित J Med Chem (2020)

Interaction with WDR5 Promotes Target Gene Recognition and Tumorigenesis by MYC

द्वारा Thomas, Lance R., Wang, Qingguo, Grieb, Brian C., Phan, Jason, Foshage, Audra M., Sun, Qi, Olejniczak, Edward T., Clark, Travis, Dey, Soumyadeep, Lorey, Shelly, Alicie, Bethany, Howard, Gregory C., Cawthon, Bryan, Ess, Kevin C., Eischen, Christine M., Zhao, Zhongming, Fesik, Stephen W., Tansey, William P.
में प्रकाशित Mol Cell (2015)

Discovery of Potent 2-Aryl-6,7-Dihydro-5H-Pyrrolo[1,2-a]imidazoles as WDR5 WIN-site Inhibitors Using Fragment-Based Methods and Structure-Based Design

द्वारा Wang, Feng, Jeon, Kyu Ok, Salovich, James M., Macdonald, Jonathan D., Alvarado, Joseph, Gogliotti, Rocco D., Phan, Jason, Olejniczak, Edward T., Sun, Qi, Wang, Shidong, Camper, DeMarco, Yuh, Joannes P., Shaw, J. Grace, Sai, Jiqing, Rossanese, Olivia W., Tansey, William P., Stauffer, Shaun R., Fesik, Stephen W.
में प्रकाशित J Med Chem (2018)

Discovery and Structure-Based Optimization of Benzimidazole-Derived Activators of SOS1-Mediated Nucleotide Exchange on RAS

द्वारा Hodges, Timothy R., Abbott, Jason R., Little, Andrew J., Sarkar, Dhruba, Salovich, James M., Howes, Jennifer E., Akan, Denis T., Sai, Jiqing, Arnold, Allison L., Browning, Carrie, Burns, Michael C., Sobolik, Tammy, Sun, Qi, Beesetty, Yugandhar, Coker, Jesse A., Scharn, Dirk, Stadtmueller, Heinz, Rossanese, Olivia W., Phan, Jason, Waterson, Alex G., McConnell, Darryl B., Fesik, Stephen W.
में प्रकाशित J Med Chem (2018)

Discovery and Optimization of Salicylic Acid-Derived Sulfonamide Inhibitors of the WD Repeat-Containing Protein 5 (WDR5)–MYC Protein–Protein Interaction

द्वारा Macdonald, Jonathan D., Simon, Selena Chacón, Han, Changho, Wang, Feng, Shaw, J. Grace, Howes, Jennifer E., Sai, Jiqing, Yuh, Joannes P., Camper, Demarco, Alicie, Bethany M., Alvarado, Joseph, Nikhar, Sameer, Payne, William, Aho, Erin R., Bauer, Joshua A., Zhao, Bin, Phan, Jason, Thomas, Lance R., Rossanese, Olivia W., Tansey, William P., Waterson, Alex G., Stauffer, Shaun R., Fesik, Stephen W.
में प्रकाशित J Med Chem (2019)

Displacement of WDR5 from Chromatin by a WIN Site Inhibitor with Picomolar Affinity

द्वारा Aho, Erin R., Wang, Jing, Gogliotti, Rocco D., Howard, Gregory C., Phan, Jason, Acharya, Pankaj, Macdonald, Jonathan D., Cheng, Ken, Lorey, Shelly L., Lu, Bin, Wenzel, Sabine, Foshage, Audra M., Alvarado, Joseph, Wang, Feng, Shaw, J. Grace, Zhao, Bin, Weissmiller, April M., Thomas, Lance R., Vakoc, Christopher R., Hall, Matthew D., Hiebert, Scott W., Liu, Qi, Stauffer, Shaun R., Fesik, Stephen W., Tansey, William P.
में प्रकाशित Cell Rep (2019)

Drugging an undruggable pocket on KRAS

द्वारा Kessler, Dirk, Gmachl, Michael, Mantoulidis, Andreas, Martin, Laetitia J., Zoephel, Andreas, Mayer, Moriz, Gollner, Andreas, Covini, David, Fischer, Silke, Gerstberger, Thomas, Gmaschitz, Teresa, Goodwin, Craig, Greb, Peter, Häring, Daniela, Hela, Wolfgang, Hoffmann, Johann, Karolyi-Oezguer, Jale, Knesl, Petr, Kornigg, Stefan, Koegl, Manfred, Kousek, Roland, Lamarre, Lyne, Moser, Franziska, Munico-Martinez, Silvia, Peinsipp, Christoph, Phan, Jason, Rinnenthal, Jörg, Sai, Jiqing, Salamon, Christian, Scherbantin, Yvonne, Schipany, Katharina, Schnitzer, Renate, Schrenk, Andreas, Sharps, Bernadette, Siszler, Gabriella, Sun, Qi, Waterson, Alex, Wolkerstorfer, Bernhard, Zeeb, Markus, Pearson, Mark, Fesik, Stephen W., McConnell, Darryl B.
में प्रकाशित Proc Natl Acad Sci U S A (2019)

Reply to Tran et al.: Dimeric KRAS protein–protein interaction stabilizers

द्वारा Kessler, Dirk, Gollner, Andreas, Gmachl, Michael, Mantoulidis, Andreas, Martin, Laetitia J., Zoephel, Andreas, Mayer, Moriz, Covini, David, Fischer, Silke, Gerstberger, Thomas, Gmaschitz, Teresa, Goodwin, Craig, Greb, Peter, Häring, Daniela, Hela, Wolfgang, Hoffmann, Johann, Karolyi-Oezguer, Jale, Knesl, Petr, Kornigg, Stefan, Koegl, Manfred, Kousek, Roland, Lamarre, Lyne, Moser, Franziska, Munico-Martinez, Silvia, Peinsipp, Christoph, Phan, Jason, Rinnenthal, Jörg, Sai, Jiqing, Salamon, Christian, Scherbantin, Yvonne, Schipany, Katharina, Schnitzer, Renate, Schrenk, Andreas, Sharps, Bernadette, Siszler, Gabriella, Sun, Qi, Waterson, Alex, Wolkerstorfer, Bernhard, Zeeb, Markus, Pearson, Mark, Fesik, Stephen W., McConnell, Darryl B.
में प्रकाशित Proc Natl Acad Sci U S A (2020)