Heterologous desensitization of cardiac β-adrenergic signal via hormone-induced βAR/arrestin/PDE4 complexes

AIMS: Cardiac β-adrenergic receptor (βAR) signalling is susceptible to heterologous desensitization by different neurohormonal stimuli in clinical conditions associated with heart failure. We aim to examine the underlying mechanism of cross talk between βARs and a set of G-protein coupled receptors...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Cardiovasc Res
Main Authors: Shi, Qian, Li, Minghui, Mika, Delphine, Fu, Qin, Kim, Sungjin, Phan, Jason, Shen, Ao, Vandecasteele, Gregoire, Xiang, Yang K.
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2017
Teme:
Original Articles
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5852637/
https://ncbi.nlm.nih.gov/pubmed/28339772
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/cvr/cvx036
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