S-nitrosylation of β-arrestin regulates β-adrenergic receptor trafficking

Signal transduction through G protein-coupled receptors (GPCRs) is regulated by receptor desensitization and internalization that follow agonist stimulation. Nitric oxide (NO) can influence these processes, but the cellular source of NO bioactivity and the effects of NO on GPCR-mediated signal trans...

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Main Authors: Ozawa, Kentaro, Whalen, Erin J., Nelson, Christopher D., Mu, Yuanyu, Hess, Douglas T., Lefkowitz, Robert J., Stamler, Jonathan S.
Format: Artigo
Jezik:Inglês
Izdano: 2008
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2630185/
https://ncbi.nlm.nih.gov/pubmed/18691971
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2008.05.024
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