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β-arrestin-mediated receptor trafficking and signal transduction
β-arrestins function as endocytic adaptors and mediate trafficking of a variety of cell-surface receptors, including seven-transmembrane receptors (7TMRs). In the case of 7TMRs, β-arrestins carry out these tasks while simultaneously inhibiting upstream G protein-dependent signaling and promoting alt...
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| Main Authors: | , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2011
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3159699/ https://ncbi.nlm.nih.gov/pubmed/21680031 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tips.2011.05.002 |
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