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NHERF1 Regulates Parathyroid Hormone Receptor Desensitization: Interference with β-Arrestin Binding

Type 1 parathyroid hormone receptor (PTH1R) activation, desensitization, internalization, and recycling proceed in a cyclical manner. The Na(+)/H(+) exchange regulatory factor 1 (NHERF1) is a cytoplasmic adapter protein that regulates trafficking and signaling of several G protein-coupled receptors...

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Bibliografske podrobnosti
Main Authors: Wang, Bin, Yang, Yanmei, Abou-Samra, Abdul B., Friedman, Peter A.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Pharmacology and Experimental Therapeutics 2009
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2672812/
https://ncbi.nlm.nih.gov/pubmed/19188335
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/mol.108.054486
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