Current advances in using neurotrophic factors to treat neurodegenerative disorders

Por Weissmiller, April M, Wu, Chengbiao
Publicado em 2012

Enhanced β-secretase processing alters APP axonal transport and leads to axonal defects

Por Rodrigues, Elizabeth M., Weissmiller, April M., Goldstein, Lawrence S.B.
Publicado em 2012

The MYC–WDR5 Nexus and Cancer

Por Thomas, Lance R., Foshage, Audra M., Weissmiller, April M., Tansey, William P.
Publicado no Cancer Res (2015)

Targeting WDR5: A WINning Anti-Cancer Strategy?

Por Aho, Erin R, Weissmiller, April M, Fesik, Stephen W, Tansey, William P
Publicado no Epigenet Insights (2019)

Real-time Imaging of Axonal Transport of Quantum Dot-labeled BDNF in Primary Neurons

Por Zhao, Xiaobei, Zhou, Yue, Weissmiller, April M., Pearn, Matthew L., Mobley, William C., Wu, Chengbiao
Publicado no J Vis Exp (2014)

Inhibition of MYC by the SMARCB1 tumor suppressor

Por Weissmiller, April M., Wang, Jing, Lorey, Shelly L., Howard, Gregory C., Martinez, Ernest, Liu, Qi, Tansey, William P.
Publicado no Nat Commun (2019)

Functional Impact of Corticotropin-Releasing Factor Exposure on Tau Phosphorylation and Axon Transport

Por Le, Michelle H., Weissmiller, April M., Monte, Louise, Lin, Po Han, Hexom, Tia C., Natera, Orlangie, Wu, Chengbiao, Rissman, Robert A.
Publicado no PLoS One (2016)

Rat embryonic hippocampus and induced pluripotent stem cell derived cultured neurons recover from laser-induced subaxotomy

Por Selfridge, Aaron, Hyun, Nicholas, Chiang, Chai-Chun, Reyna, Sol M., Weissmiller, April M., Shi, Linda Z., Preece, Daryl, Mobley, William C., Berns, Michael W.
Publicado no Neurophotonics (2015)

Interaction of the oncoprotein transcription factor MYC with its chromatin cofactor WDR5 is essential for tumor maintenance

Por Thomas, Lance R., Adams, Clare M., Wang, Jing, Weissmiller, April M., Creighton, Joy, Lorey, Shelly L., Liu, Qi, Fesik, Stephen W., Eischen, Christine M., Tansey, William P.
Publicado no Proc Natl Acad Sci U S A (2019)

Interaction of MYC with Host Cell Factor-1 is meditated by the evolutionarily-conserved Myc box IV motif

Por Thomas, Lance R., Foshage, Audra M., Weissmiller, April M., Popay, Tessa M., Grieb, Brian C., Qualls, Susan J., Ng, Victoria, Carboneau, Bethany, Lorey, Shelly, Eischen, Christine M., Tansey, William P.
Publicado no Oncogene (2015)

A γ-Secretase Inhibitor, but Not a γ-Secretase Modulator, Induced Defects in BDNF Axonal Trafficking and Signaling: Evidence for a Role for APP

Por Weissmiller, April M., Natera-Naranjo, Orlangie, Reyna, Sol M., Pearn, Matthew L., Zhao, Xiaobei, Nguyen, Phuong, Cheng, Soan, Goldstein, Lawrence S. B., Tanzi, Rudolph E., Wagner, Steven L., Mobley, William C., Wu, Chengbiao
Publicado no PLoS One (2015)

Amyloid precursor protein–mediated endocytic pathway disruption induces axonal dysfunction and neurodegeneration

Por Xu, Wei, Weissmiller, April M., White, Joseph A., Fang, Fang, Wang, Xinyi, Wu, Yiwen, Pearn, Matthew L., Zhao, Xiaobei, Sawa, Mariko, Chen, Shengdi, Gunawardena, Shermali, Ding, Jianqing, Mobley, William C., Wu, Chengbiao
Publicado no J Clin Invest (2016)

MYC regulates ribosome biogenesis and mitochondrial gene expression programs through its interaction with host cell factor–1

Por Popay, Tessa M, Wang, Jing, Adams, Clare M, Howard, Gregory Caleb, Codreanu, Simona G, Sherrod, Stacy D, McLean, John A, Thomas, Lance R, Lorey, Shelly L, Machida, Yuichi J, Weissmiller, April M, Eischen, Christine M, Liu, Qi, Tansey, William P
Publicado no eLife (2021)

WDR5 is a conserved regulator of protein synthesis gene expression

Por Bryan, Audra F, Wang, Jing, Howard, Gregory C, Guarnaccia, Alissa D, Woodley, Chase M, Aho, Erin R, Rellinger, Eric J, Matlock, Brittany K, Flaherty, David K, Lorey, Shelly L, Chung, Dai H, Fesik, Stephen W, Liu, Qi, Weissmiller, April M, Tansey, William P
Publicado no Nucleic Acids Res (2020)

Impact of WIN site inhibitor on the WDR5 interactome

Por Guarnaccia, Alissa D., Rose, Kristie L., Wang, Jing, Zhao, Bin, Popay, Tessa M., Wang, Christina E., Guerrazzi, Kiana, Hill, Salisha, Woodley, Chase M., Hansen, Tyler J., Lorey, Shelly L., Shaw, J. Grace, Payne, William G., Weissmiller, April M., Olejniczak, Edward T., Fesik, Stephen W., Liu, Qi, Tansey, William P.
Publicado no Cell Rep (2021)

Displacement of WDR5 from Chromatin by a WIN Site Inhibitor with Picomolar Affinity

Por Aho, Erin R., Wang, Jing, Gogliotti, Rocco D., Howard, Gregory C., Phan, Jason, Acharya, Pankaj, Macdonald, Jonathan D., Cheng, Ken, Lorey, Shelly L., Lu, Bin, Wenzel, Sabine, Foshage, Audra M., Alvarado, Joseph, Wang, Feng, Shaw, J. Grace, Zhao, Bin, Weissmiller, April M., Thomas, Lance R., Vakoc, Christopher R., Hall, Matthew D., Hiebert, Scott W., Liu, Qi, Stauffer, Shaun R., Fesik, Stephen W., Tansey, William P.
Publicado no Cell Rep (2019)