Real-time Imaging of Axonal Transport of Quantum Dot-labeled BDNF in Primary Neurons

BDNF plays an important role in several facets of neuronal survival, differentiation, and function. Structural and functional deficits in axons are increasingly viewed as an early feature of neurodegenerative diseases, including Alzheimer’s disease (AD) and Huntington’s disease (HD). As yet unclear...

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Detalhes bibliográficos
Publicado no:J Vis Exp
Main Authors: Zhao, Xiaobei, Zhou, Yue, Weissmiller, April M., Pearn, Matthew L., Mobley, William C., Wu, Chengbiao
Formato: Artigo
Idioma:Inglês
Publicado em: MyJove Corporation 2014
Assuntos:
Neuroscience
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4828072/
https://ncbi.nlm.nih.gov/pubmed/25286194
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3791/51899
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