Functional Impact of Corticotropin-Releasing Factor Exposure on Tau Phosphorylation and Axon Transport

Stress exposure or increased levels of corticotropin-releasing factor (CRF) induce hippocampal tau phosphorylation (tau-P) in rodent models, a process that is dependent on the type-1 CRF receptor (CRFR1). Although these preclinical studies on stress-induced tau-P provide mechanistic insight for epid...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Le, Michelle H., Weissmiller, April M., Monte, Louise, Lin, Po Han, Hexom, Tia C., Natera, Orlangie, Wu, Chengbiao, Rissman, Robert A.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2016
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4720402/
https://ncbi.nlm.nih.gov/pubmed/26790099
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0147250
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