Corticotropin-Releasing Factor Receptors Differentially Regulate Stress-Induced Tau Phosphorylation

Hyperphosphorylation of the microtubule-associated protein tau is a key event in the development of Alzheimer's disease (AD) neuropathology. Acute stress can induce hippocampal tau phosphorylation (tau-P) in rodents, but the mechanisms and pathogenic relevance of this response are unclear. Here...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:J Neurosci
Prif Awduron: Rissman, Robert A., Lee, Kuo-Fen, Vale, Wylie, Sawchenko, Paul E.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Society for Neuroscience 2007
Pynciau:
Articles
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6672442/
https://ncbi.nlm.nih.gov/pubmed/17567816
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.5173-06.2007
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